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Ancient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteins
BACKGROUND: Soluble guanylyl cyclases (SGCs) are dimeric enzymes that transduce signals downstream of nitric oxide (NO) in animals. They sense NO by means of a heme moiety that is bound to their N-terminal extensions. RESULTS: Using sequence profile searches we show that the N-terminal extensions of...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC149354/ https://www.ncbi.nlm.nih.gov/pubmed/12590654 http://dx.doi.org/10.1186/1471-2164-4-5 |