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Evolutionary and Physiological Importance of Hub Proteins
It has been claimed that proteins with more interaction partners (hubs) are both physiologically more important (i.e., less dispensable) and, owing to an assumed high density of binding sites, slow evolving. Not all analyses, however, support these results, probably because of biased and less-than r...
Autores principales: | Batada, Nizar N, Hurst, Laurence D, Tyers, Mike |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500817/ https://www.ncbi.nlm.nih.gov/pubmed/16839197 http://dx.doi.org/10.1371/journal.pcbi.0020088 |
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