Detecting non-orthology in the COGs database and other approaches grouping orthologs using genome-specific best hits

Correct orthology assignment is a critical prerequisite of numerous comparative genomics procedures, such as function prediction, construction of phylogenetic species trees and genome rearrangement analysis. We present an algorithm for the detection of non-orthologs that arise by mistake in current...

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Detalles Bibliográficos
Autores principales: Dessimoz, Christophe, Boeckmann, Brigitte, Roth, Alexander C. J., Gonnet, Gaston H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500873/
https://www.ncbi.nlm.nih.gov/pubmed/16835308
http://dx.doi.org/10.1093/nar/gkl433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500873/
https://www.ncbi.nlm.nih.gov/pubmed/16835308
http://dx.doi.org/10.1093/nar/gkl433

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