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Detecting non-orthology in the COGs database and other approaches grouping orthologs using genome-specific best hits
Correct orthology assignment is a critical prerequisite of numerous comparative genomics procedures, such as function prediction, construction of phylogenetic species trees and genome rearrangement analysis. We present an algorithm for the detection of non-orthologs that arise by mistake in current...
Autores principales: | Dessimoz, Christophe, Boeckmann, Brigitte, Roth, Alexander C. J., Gonnet, Gaston H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500873/ https://www.ncbi.nlm.nih.gov/pubmed/16835308 http://dx.doi.org/10.1093/nar/gkl433 |
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