Status of insecticide susceptibility in Anopheles arabiensis from Mwea rice irrigation scheme, Central Kenya
BACKGROUND: Control of the Anopheline mosquito vectors of malaria by use of insecticides has been shown to impact on both morbidity and mortality due to this disease. Evidence of insecticide resistance in different settings necessitates surveillance studies to allow prompt detection of resistance sh...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501029/ https://www.ncbi.nlm.nih.gov/pubmed/16756645 http://dx.doi.org/10.1186/1475-2875-5-46 |
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author | Kamau, Luna Vulule, John M |
author_facet | Kamau, Luna Vulule, John M |
author_sort | Kamau, Luna |
collection | PubMed |
description | BACKGROUND: Control of the Anopheline mosquito vectors of malaria by use of insecticides has been shown to impact on both morbidity and mortality due to this disease. Evidence of insecticide resistance in different settings necessitates surveillance studies to allow prompt detection of resistance should it arise and thus enable its management. Possible resistance by Anopheles arabiensis mosquitoes from Mwea rice irrigation scheme in Central Kenya to insecticides in the four classes of insecticides approved by WHO for indoor residual spraying was investigated. METHODS: Susceptibility to DDT (an organochlorine), fenitrothion (an organophosphate), bendiocarb (a carbamate), lambdacyhalothrin and permethrin (both pyrethroids) was tested using standard WHO diagnostic bioassay kits. Bioassays were performed on non-blood fed mosquitoes one- to three-day old. Knockdown was recorded every 10 min and mortality 24 h post-exposure was noted. RESULTS: Mortality 24 h post-exposure was 100% for all insecticides except for lambdacyhalothrin, which averaged 99.46%. Knockdown rates at 10 min intervals were not significantly different between the Mwea population and the susceptible KISUMU strain of Anopheles gambiae sensu stricto control. The KDT(50 )and KDT(95 )values for the Mwea population were either lower than those for the control or higher by factors of no more than 2 for most comparisons and compared well with those of An. gambiae sensu lato categorized as susceptible in other studies. CONCLUSION: These results suggest that the Mwea population of An. arabiensis is susceptible to all the insecticides tested. This implies that vector control measures employing any of these insecticides would not be hampered by resistance. |
format | Text |
id | pubmed-1501029 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-15010292006-07-13 Status of insecticide susceptibility in Anopheles arabiensis from Mwea rice irrigation scheme, Central Kenya Kamau, Luna Vulule, John M Malar J Research BACKGROUND: Control of the Anopheline mosquito vectors of malaria by use of insecticides has been shown to impact on both morbidity and mortality due to this disease. Evidence of insecticide resistance in different settings necessitates surveillance studies to allow prompt detection of resistance should it arise and thus enable its management. Possible resistance by Anopheles arabiensis mosquitoes from Mwea rice irrigation scheme in Central Kenya to insecticides in the four classes of insecticides approved by WHO for indoor residual spraying was investigated. METHODS: Susceptibility to DDT (an organochlorine), fenitrothion (an organophosphate), bendiocarb (a carbamate), lambdacyhalothrin and permethrin (both pyrethroids) was tested using standard WHO diagnostic bioassay kits. Bioassays were performed on non-blood fed mosquitoes one- to three-day old. Knockdown was recorded every 10 min and mortality 24 h post-exposure was noted. RESULTS: Mortality 24 h post-exposure was 100% for all insecticides except for lambdacyhalothrin, which averaged 99.46%. Knockdown rates at 10 min intervals were not significantly different between the Mwea population and the susceptible KISUMU strain of Anopheles gambiae sensu stricto control. The KDT(50 )and KDT(95 )values for the Mwea population were either lower than those for the control or higher by factors of no more than 2 for most comparisons and compared well with those of An. gambiae sensu lato categorized as susceptible in other studies. CONCLUSION: These results suggest that the Mwea population of An. arabiensis is susceptible to all the insecticides tested. This implies that vector control measures employing any of these insecticides would not be hampered by resistance. BioMed Central 2006-06-06 /pmc/articles/PMC1501029/ /pubmed/16756645 http://dx.doi.org/10.1186/1475-2875-5-46 Text en Copyright © 2006 Kamau and Vulule; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Kamau, Luna Vulule, John M Status of insecticide susceptibility in Anopheles arabiensis from Mwea rice irrigation scheme, Central Kenya |
title | Status of insecticide susceptibility in Anopheles arabiensis from Mwea rice irrigation scheme, Central Kenya |
title_full | Status of insecticide susceptibility in Anopheles arabiensis from Mwea rice irrigation scheme, Central Kenya |
title_fullStr | Status of insecticide susceptibility in Anopheles arabiensis from Mwea rice irrigation scheme, Central Kenya |
title_full_unstemmed | Status of insecticide susceptibility in Anopheles arabiensis from Mwea rice irrigation scheme, Central Kenya |
title_short | Status of insecticide susceptibility in Anopheles arabiensis from Mwea rice irrigation scheme, Central Kenya |
title_sort | status of insecticide susceptibility in anopheles arabiensis from mwea rice irrigation scheme, central kenya |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501029/ https://www.ncbi.nlm.nih.gov/pubmed/16756645 http://dx.doi.org/10.1186/1475-2875-5-46 |
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