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The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management
Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia, exercise intolerance, lightheadedness, extrem...
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Formato: | Texto |
Lenguaje: | English |
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Indian Pacing and Electrophysiology Group
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501099/ https://www.ncbi.nlm.nih.gov/pubmed/16943900 |
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author | Raj, Satish R |
author_facet | Raj, Satish R |
author_sort | Raj, Satish R |
collection | PubMed |
description | Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia, exercise intolerance, lightheadedness, extreme fatigue, headache and mental clouding. Patients with POTS demonstrate a heart rate increase of ≥30 bpm with prolonged standing (5-30 minutes), often have high levels of upright plasma norepinephrine (reflecting sympathetic nervous system activation), and many patients have a low blood volume. POTS can be associated with a high degree of functional disability. Therapies aimed at correcting the hypovolemia and the autonomic imbalance may help relieve the severity of the symptoms. This review outlines the present understanding of the pathophysiology, diagnosis, and management of POTS. |
format | Text |
id | pubmed-1501099 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | Indian Pacing and Electrophysiology Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-15010992006-08-29 The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management Raj, Satish R Indian Pacing Electrophysiol J Reviews Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia, exercise intolerance, lightheadedness, extreme fatigue, headache and mental clouding. Patients with POTS demonstrate a heart rate increase of ≥30 bpm with prolonged standing (5-30 minutes), often have high levels of upright plasma norepinephrine (reflecting sympathetic nervous system activation), and many patients have a low blood volume. POTS can be associated with a high degree of functional disability. Therapies aimed at correcting the hypovolemia and the autonomic imbalance may help relieve the severity of the symptoms. This review outlines the present understanding of the pathophysiology, diagnosis, and management of POTS. Indian Pacing and Electrophysiology Group 2006-04-01 /pmc/articles/PMC1501099/ /pubmed/16943900 Text en Copyright: © 2006 Raj http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Raj, Satish R The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management |
title | The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management |
title_full | The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management |
title_fullStr | The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management |
title_full_unstemmed | The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management |
title_short | The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management |
title_sort | postural tachycardia syndrome (pots): pathophysiology, diagnosis & management |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501099/ https://www.ncbi.nlm.nih.gov/pubmed/16943900 |
work_keys_str_mv | AT rajsatishr theposturaltachycardiasyndromepotspathophysiologydiagnosismanagement AT rajsatishr posturaltachycardiasyndromepotspathophysiologydiagnosismanagement |