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The Role of Anabolic Hormones for Wound Healing in Catabolic States
Objective: The purpose of this paper is to present an overview of the interrelationship between hormones, nutrition, and wound healing. Methods: The data on various hormones and their effects on specific elements of nutrition and wound healing are reviewed. Results: The key anabolic hormones are hum...
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Formato: | Texto |
Lenguaje: | English |
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Open Science Company, LLC
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501119/ https://www.ncbi.nlm.nih.gov/pubmed/16921407 |
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author | Demling, Robert H. |
author_facet | Demling, Robert H. |
author_sort | Demling, Robert H. |
collection | PubMed |
description | Objective: The purpose of this paper is to present an overview of the interrelationship between hormones, nutrition, and wound healing. Methods: The data on various hormones and their effects on specific elements of nutrition and wound healing are reviewed. Results: The key anabolic hormones are human growth hormone, insulin-like growth factor-1, insulin, and testosterone and its analogs. Although each has specific metabolic actions, there is also a very important hormone-hormone interaction. A deficiency of these hormones occurs in acute and chronic catabolic states, resulting in lean mass loss and impairing the healing process. Conclusion: There is a well-recognized interrelationship between hormones, nutrition, and wound healing. The anabolic process of protein synthesis, with new tissue formation, requires the action of anabolic hormones. Exogenous administration of these agents has been shown to maintain or increase lean body mass as well as directly stimulate the healing process through their anabolic and anticatabolic actions. |
format | Text |
id | pubmed-1501119 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | Open Science Company, LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-15011192006-08-17 The Role of Anabolic Hormones for Wound Healing in Catabolic States Demling, Robert H. J Burns Wounds Article Objective: The purpose of this paper is to present an overview of the interrelationship between hormones, nutrition, and wound healing. Methods: The data on various hormones and their effects on specific elements of nutrition and wound healing are reviewed. Results: The key anabolic hormones are human growth hormone, insulin-like growth factor-1, insulin, and testosterone and its analogs. Although each has specific metabolic actions, there is also a very important hormone-hormone interaction. A deficiency of these hormones occurs in acute and chronic catabolic states, resulting in lean mass loss and impairing the healing process. Conclusion: There is a well-recognized interrelationship between hormones, nutrition, and wound healing. The anabolic process of protein synthesis, with new tissue formation, requires the action of anabolic hormones. Exogenous administration of these agents has been shown to maintain or increase lean body mass as well as directly stimulate the healing process through their anabolic and anticatabolic actions. Open Science Company, LLC 2005-01-17 /pmc/articles/PMC1501119/ /pubmed/16921407 Text en Copyright © 2005 The Author http://creativecommons.org/licenses/by/2.0/ This is an open-access article whereby the authors retain copyright of the work. The article is distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Demling, Robert H. The Role of Anabolic Hormones for Wound Healing in Catabolic States |
title | The Role of Anabolic Hormones for Wound Healing in Catabolic States |
title_full | The Role of Anabolic Hormones for Wound Healing in Catabolic States |
title_fullStr | The Role of Anabolic Hormones for Wound Healing in Catabolic States |
title_full_unstemmed | The Role of Anabolic Hormones for Wound Healing in Catabolic States |
title_short | The Role of Anabolic Hormones for Wound Healing in Catabolic States |
title_sort | role of anabolic hormones for wound healing in catabolic states |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501119/ https://www.ncbi.nlm.nih.gov/pubmed/16921407 |
work_keys_str_mv | AT demlingroberth theroleofanabolichormonesforwoundhealingincatabolicstates AT demlingroberth roleofanabolichormonesforwoundhealingincatabolicstates |