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Apolipoprotein E-specific innate immune response in astrocytes from targeted replacement mice
BACKGROUND: Inheritance of the three different alleles of the human apolipoprotein (apo) E gene (APOE) are associated with varying risk or clinical outcome from a variety of neurologic diseases. ApoE isoform-specific modulation of several pathogenic processes, in addition to amyloid β metabolism in...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1502133/ https://www.ncbi.nlm.nih.gov/pubmed/16603079 http://dx.doi.org/10.1186/1742-2094-3-10 |