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Apolipoprotein E-specific innate immune response in astrocytes from targeted replacement mice

BACKGROUND: Inheritance of the three different alleles of the human apolipoprotein (apo) E gene (APOE) are associated with varying risk or clinical outcome from a variety of neurologic diseases. ApoE isoform-specific modulation of several pathogenic processes, in addition to amyloid β metabolism in...

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Detalles Bibliográficos
Autores principales:	Maezawa, Izumi, Maeda, Nobuyo, Montine, Thomas J, Montine, Kathleen S
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1502133/ https://www.ncbi.nlm.nih.gov/pubmed/16603079 http://dx.doi.org/10.1186/1742-2094-3-10

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