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Impaired germ cell development due to compromised cell cycle progression in Skp2-deficient mice
BACKGROUND: The gonads are responsible for the production of germ cells through both mitosis and meiosis. Skp2 is the receptor subunit of an SCF-type ubiquitin ligase and is a major regulator of the progression of cells into S phase of the cell cycle, which it promotes by mediating the ubiquitin-dep...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1502135/ https://www.ncbi.nlm.nih.gov/pubmed/16759351 http://dx.doi.org/10.1186/1747-1028-1-4 |