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Insensitivity of Paediatric HIV-1 Subtype C Viruses to Broadly Neutralising Monoclonal Antibodies Raised against Subtype B

BACKGROUND: A Phase I clinical trial has been proposed that uses neutralising monoclonal antibodies (MAbs) as passive immunoprophylaxis to prevent mother-to-child transmission of HIV-1 in South Africa. To assess the suitability of such an approach, we determined the sensitivity of paediatric HIV-1 s...

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Detalles Bibliográficos
Autores principales:	Gray, Elin Solomonovna, Meyers, Tammy, Gray, Glenda, Montefiori, David Charles, Morris, Lynn
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1502151/ https://www.ncbi.nlm.nih.gov/pubmed/16834457 http://dx.doi.org/10.1371/journal.pmed.0030255

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