Genome sequences and great expectations

To assess how automatic function assignment will contribute to genome annotation in the next five years, we have performed an analysis of 31 available genome sequences. An emerging pattern is that function can be predicted for almost two-thirds of the 73,500 genes that were analyzed. Despite progres...

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Detalles Bibliográficos
Autores principales: Iliopoulos, Ioannis, Tsoka, Sophia, Andrade, Miguel A, Janssen, Paul, Audit, Benjamin, Tramontano, Anna, Valencia, Alfonso, Leroy, Christophe, Sander, Chris, Ouzounis, Christos A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Open Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150431/
https://www.ncbi.nlm.nih.gov/pubmed/11178275
Descripción
Sumario:To assess how automatic function assignment will contribute to genome annotation in the next five years, we have performed an analysis of 31 available genome sequences. An emerging pattern is that function can be predicted for almost two-thirds of the 73,500 genes that were analyzed. Despite progress in computational biology, there will always be a great need for large-scale experimental determination of protein function.

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