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DNA replication: telling time with microarrays

A long-standing hypothesis about eukaryotic DNA replication is that the late-replicating regions are transcriptionally inert and that repressing transcription delays replication initiation. But do contrasting results from yeast and a recent study in Drosophila imply that replication timing and trans...

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Detalles Bibliográficos
Autores principales: McCune, Heather J, Donaldson, Anne D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151294/
https://www.ncbi.nlm.nih.gov/pubmed/12620111
http://dx.doi.org/10.1186/gb-2003-4-2-204
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author McCune, Heather J
Donaldson, Anne D
author_facet McCune, Heather J
Donaldson, Anne D
author_sort McCune, Heather J
collection PubMed
description A long-standing hypothesis about eukaryotic DNA replication is that the late-replicating regions are transcriptionally inert and that repressing transcription delays replication initiation. But do contrasting results from yeast and a recent study in Drosophila imply that replication timing and transcriptional activity are differentially regulated in yeast and higher eukaryotes?
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spelling pubmed-1512942003-03-13 DNA replication: telling time with microarrays McCune, Heather J Donaldson, Anne D Genome Biol Minireview A long-standing hypothesis about eukaryotic DNA replication is that the late-replicating regions are transcriptionally inert and that repressing transcription delays replication initiation. But do contrasting results from yeast and a recent study in Drosophila imply that replication timing and transcriptional activity are differentially regulated in yeast and higher eukaryotes? BioMed Central 2003 2003-01-30 /pmc/articles/PMC151294/ /pubmed/12620111 http://dx.doi.org/10.1186/gb-2003-4-2-204 Text en Copyright © 2003 BioMed Central Ltd
spellingShingle Minireview
McCune, Heather J
Donaldson, Anne D
DNA replication: telling time with microarrays
title DNA replication: telling time with microarrays
title_full DNA replication: telling time with microarrays
title_fullStr DNA replication: telling time with microarrays
title_full_unstemmed DNA replication: telling time with microarrays
title_short DNA replication: telling time with microarrays
title_sort dna replication: telling time with microarrays
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151294/
https://www.ncbi.nlm.nih.gov/pubmed/12620111
http://dx.doi.org/10.1186/gb-2003-4-2-204
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