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DNA replication: telling time with microarrays
A long-standing hypothesis about eukaryotic DNA replication is that the late-replicating regions are transcriptionally inert and that repressing transcription delays replication initiation. But do contrasting results from yeast and a recent study in Drosophila imply that replication timing and trans...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151294/ https://www.ncbi.nlm.nih.gov/pubmed/12620111 http://dx.doi.org/10.1186/gb-2003-4-2-204 |
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author | McCune, Heather J Donaldson, Anne D |
author_facet | McCune, Heather J Donaldson, Anne D |
author_sort | McCune, Heather J |
collection | PubMed |
description | A long-standing hypothesis about eukaryotic DNA replication is that the late-replicating regions are transcriptionally inert and that repressing transcription delays replication initiation. But do contrasting results from yeast and a recent study in Drosophila imply that replication timing and transcriptional activity are differentially regulated in yeast and higher eukaryotes? |
format | Text |
id | pubmed-151294 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2003 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-1512942003-03-13 DNA replication: telling time with microarrays McCune, Heather J Donaldson, Anne D Genome Biol Minireview A long-standing hypothesis about eukaryotic DNA replication is that the late-replicating regions are transcriptionally inert and that repressing transcription delays replication initiation. But do contrasting results from yeast and a recent study in Drosophila imply that replication timing and transcriptional activity are differentially regulated in yeast and higher eukaryotes? BioMed Central 2003 2003-01-30 /pmc/articles/PMC151294/ /pubmed/12620111 http://dx.doi.org/10.1186/gb-2003-4-2-204 Text en Copyright © 2003 BioMed Central Ltd |
spellingShingle | Minireview McCune, Heather J Donaldson, Anne D DNA replication: telling time with microarrays |
title | DNA replication: telling time with microarrays |
title_full | DNA replication: telling time with microarrays |
title_fullStr | DNA replication: telling time with microarrays |
title_full_unstemmed | DNA replication: telling time with microarrays |
title_short | DNA replication: telling time with microarrays |
title_sort | dna replication: telling time with microarrays |
topic | Minireview |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151294/ https://www.ncbi.nlm.nih.gov/pubmed/12620111 http://dx.doi.org/10.1186/gb-2003-4-2-204 |
work_keys_str_mv | AT mccuneheatherj dnareplicationtellingtimewithmicroarrays AT donaldsonanned dnareplicationtellingtimewithmicroarrays |