A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses

The interaction of ERα and ERβ with ERE constitutes the initial step in the canonical nuclear E2 signaling in which E2-ERβ is a weaker transactivator than E2-ERα. This perspective summarizes recent findings to discuss potential mechanisms that contribute to ER subtype-specific transcriptional respon...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Jing, Li, Xiaodong, Qiao, Tao, Bambara, Robert A., Hilf, Russell, Muyan, Mesut
Formato: Texto
Lenguaje:English
Publicado: The Nuclear Receptor Signaling Atlas 2006
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513069/
https://www.ncbi.nlm.nih.gov/pubmed/16862221
http://dx.doi.org/10.1621/nrs.04015
_version_ 1782128446340595712
author Huang, Jing
Li, Xiaodong
Qiao, Tao
Bambara, Robert A.
Hilf, Russell
Muyan, Mesut
author_facet Huang, Jing
Li, Xiaodong
Qiao, Tao
Bambara, Robert A.
Hilf, Russell
Muyan, Mesut
author_sort Huang, Jing
collection PubMed
description The interaction of ERα and ERβ with ERE constitutes the initial step in the canonical nuclear E2 signaling in which E2-ERβ is a weaker transactivator than E2-ERα. This perspective summarizes recent findings to discuss potential mechanisms that contribute to ER subtype-specific transcriptional responses.
format Text
id pubmed-1513069
institution National Center for Biotechnology Information
language English
publishDate 2006
publisher The Nuclear Receptor Signaling Atlas
record_format MEDLINE/PubMed
spelling pubmed-15130692006-07-20 A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses Huang, Jing Li, Xiaodong Qiao, Tao Bambara, Robert A. Hilf, Russell Muyan, Mesut Nucl Recept Signal Perspective The interaction of ERα and ERβ with ERE constitutes the initial step in the canonical nuclear E2 signaling in which E2-ERβ is a weaker transactivator than E2-ERα. This perspective summarizes recent findings to discuss potential mechanisms that contribute to ER subtype-specific transcriptional responses. The Nuclear Receptor Signaling Atlas 2006-07-07 /pmc/articles/PMC1513069/ /pubmed/16862221 http://dx.doi.org/10.1621/nrs.04015 Text en Copyright © 2006, Huang et al. This is an open-access article distributed under the terms of the Creative Commons Non-Commercial Attribution License, which permits unrestricted non-commercial use distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Perspective
Huang, Jing
Li, Xiaodong
Qiao, Tao
Bambara, Robert A.
Hilf, Russell
Muyan, Mesut
A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses
title A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses
title_full A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses
title_fullStr A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses
title_full_unstemmed A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses
title_short A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses
title_sort tale of two estrogen receptors (ers): how differential er-estrogen responsive element interactions contribute to subtype-specific transcriptional responses
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513069/
https://www.ncbi.nlm.nih.gov/pubmed/16862221
http://dx.doi.org/10.1621/nrs.04015
work_keys_str_mv AT huangjing ataleoftwoestrogenreceptorsershowdifferentialerestrogenresponsiveelementinteractionscontributetosubtypespecifictranscriptionalresponses
AT lixiaodong ataleoftwoestrogenreceptorsershowdifferentialerestrogenresponsiveelementinteractionscontributetosubtypespecifictranscriptionalresponses
AT qiaotao ataleoftwoestrogenreceptorsershowdifferentialerestrogenresponsiveelementinteractionscontributetosubtypespecifictranscriptionalresponses
AT bambararoberta ataleoftwoestrogenreceptorsershowdifferentialerestrogenresponsiveelementinteractionscontributetosubtypespecifictranscriptionalresponses
AT hilfrussell ataleoftwoestrogenreceptorsershowdifferentialerestrogenresponsiveelementinteractionscontributetosubtypespecifictranscriptionalresponses
AT muyanmesut ataleoftwoestrogenreceptorsershowdifferentialerestrogenresponsiveelementinteractionscontributetosubtypespecifictranscriptionalresponses
AT huangjing taleoftwoestrogenreceptorsershowdifferentialerestrogenresponsiveelementinteractionscontributetosubtypespecifictranscriptionalresponses
AT lixiaodong taleoftwoestrogenreceptorsershowdifferentialerestrogenresponsiveelementinteractionscontributetosubtypespecifictranscriptionalresponses
AT qiaotao taleoftwoestrogenreceptorsershowdifferentialerestrogenresponsiveelementinteractionscontributetosubtypespecifictranscriptionalresponses
AT bambararoberta taleoftwoestrogenreceptorsershowdifferentialerestrogenresponsiveelementinteractionscontributetosubtypespecifictranscriptionalresponses
AT hilfrussell taleoftwoestrogenreceptorsershowdifferentialerestrogenresponsiveelementinteractionscontributetosubtypespecifictranscriptionalresponses
AT muyanmesut taleoftwoestrogenreceptorsershowdifferentialerestrogenresponsiveelementinteractionscontributetosubtypespecifictranscriptionalresponses

Ejemplares similares