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Presenilin-dependent intramembrane cleavage of ephrin-B1

BACKGROUND: Presenilin-dependent γ-secretase cleavage of several transmembrane proteins, including amyloid-β precursor protein and Notch, mediates the intramembrane proteolysis to liberate their intracellular domains that are involved in cellular signaling. Considering γ-secretase inhibitors as ther...

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Detalles Bibliográficos
Autores principales:	Tomita, Taisuke, Tanaka, Sayaka, Morohashi, Yuichi, Iwatsubo, Takeshi
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513130/ https://www.ncbi.nlm.nih.gov/pubmed/16930449 http://dx.doi.org/10.1186/1750-1326-1-2

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