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Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel γ-secretase substrates
BACKGROUND: The mammalian Vps10p sorting receptor family is a group of 5 type I membrane homologs (Sortilin, SorLA, and SorCS1-3). These receptors bind various cargo proteins via their luminal Vps10p domains and have been shown to mediate a variety of intracellular sorting and trafficking functions....
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513133/ https://www.ncbi.nlm.nih.gov/pubmed/16930450 http://dx.doi.org/10.1186/1750-1326-1-3 |