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Predicting population coverage of T-cell epitope-based diagnostics and vaccines
BACKGROUND: T cells recognize a complex between a specific major histocompatibility complex (MHC) molecule and a particular pathogen-derived epitope. A given epitope will elicit a response only in individuals that express an MHC molecule capable of binding that particular epitope. MHC molecules are...
Autores principales: | Bui, Huynh-Hoa, Sidney, John, Dinh, Kenny, Southwood, Scott, Newman, Mark J, Sette, Alessandro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513259/ https://www.ncbi.nlm.nih.gov/pubmed/16545123 http://dx.doi.org/10.1186/1471-2105-7-153 |
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