Molecular Determinants of Ebola Virus Virulence in Mice

Zaire ebolavirus (ZEBOV) causes severe hemorrhagic fever in humans and nonhuman primates, with fatality rates in humans of up to 90%. The molecular basis for the extreme virulence of ZEBOV remains elusive. While adult mice resist ZEBOV infection, the Mayinga strain of the virus has been adapted to c...

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Detalles Bibliográficos
Autores principales: Ebihara, Hideki, Takada, Ayato, Kobasa, Darwyn, Jones, Steven, Neumann, Gabriele, Theriault, Steven, Bray, Mike, Feldmann, Heinz, Kawaoka, Yoshihiro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513261/
https://www.ncbi.nlm.nih.gov/pubmed/16848640
http://dx.doi.org/10.1371/journal.ppat.0020073

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