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Benchmarking pK(a )prediction

BACKGROUND: pK(a )values are a measure of the protonation of ionizable groups in proteins. Ionizable groups are involved in intra-protein, protein-solvent and protein-ligand interactions as well as solubility, protein folding and catalytic activity. The pK(a )shift of a group from its intrinsic valu...

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Detalles Bibliográficos
Autores principales:	Davies, Matthew N, Toseland, Christopher P, Moss, David S, Flower, Darren R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513386/ https://www.ncbi.nlm.nih.gov/pubmed/16749919 http://dx.doi.org/10.1186/1471-2091-7-18

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