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Investigating the basis of substrate recognition in the pC221 relaxosome

The nicking of the origin of transfer (oriT) is an essential initial step in the conjugative mobilization of plasmid DNA. In the case of staphylococcal plasmid pC221, nicking by the plasmid-specific MobA relaxase is facilitated by the DNA-binding accessory protein MobC; however, the role of MobC in...

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Detalles Bibliográficos
Autores principales: Caryl, Jamie A, Thomas, Christopher D
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513511/
https://www.ncbi.nlm.nih.gov/pubmed/16689804
http://dx.doi.org/10.1111/j.1365-2958.2006.05188.x