Optimizing amino acid substitution matrices with a local alignment kernel

BACKGROUND: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, called a local alignment kernel, that exhibits good performance for this task in combination with a support vector machine....

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Detalles Bibliográficos
Autores principales: Saigo, Hiroto, Vert, Jean-Philippe, Akutsu, Tatsuya
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513605/
https://www.ncbi.nlm.nih.gov/pubmed/16677385
http://dx.doi.org/10.1186/1471-2105-7-246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513605/
https://www.ncbi.nlm.nih.gov/pubmed/16677385
http://dx.doi.org/10.1186/1471-2105-7-246

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