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Optimizing amino acid substitution matrices with a local alignment kernel
BACKGROUND: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, called a local alignment kernel, that exhibits good performance for this task in combination with a support vector machine....
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513605/ https://www.ncbi.nlm.nih.gov/pubmed/16677385 http://dx.doi.org/10.1186/1471-2105-7-246 |