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Tomosyn Inhibits Synaptic Vesicle Priming in Caenorhabditis elegans

Caenorhabditis elegans TOM-1 is orthologous to vertebrate tomosyn, a cytosolic syntaxin-binding protein implicated in the modulation of both constitutive and regulated exocytosis. To investigate how TOM-1 regulates exocytosis of synaptic vesicles in vivo, we analyzed C. elegans tom-1 mutants. Our el...

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Detalles Bibliográficos
Autores principales: Gracheva, Elena O, Burdina, Anna O, Holgado, Andrea M, Berthelot-Grosjean, Martine, Ackley, Brian D, Hadwiger, Gayla, Nonet, Michael L, Weimer, Robby M, Richmond, Janet E
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1514790/
https://www.ncbi.nlm.nih.gov/pubmed/16895441
http://dx.doi.org/10.1371/journal.pbio.0040261