Cargando…

Tomosyn Inhibits Synaptic Vesicle Priming in Caenorhabditis elegans

Caenorhabditis elegans TOM-1 is orthologous to vertebrate tomosyn, a cytosolic syntaxin-binding protein implicated in the modulation of both constitutive and regulated exocytosis. To investigate how TOM-1 regulates exocytosis of synaptic vesicles in vivo, we analyzed C. elegans tom-1 mutants. Our el...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gracheva, Elena O, Burdina, Anna O, Holgado, Andrea M, Berthelot-Grosjean, Martine, Ackley, Brian D, Hadwiger, Gayla, Nonet, Michael L, Weimer, Robby M, Richmond, Janet E
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1514790/ https://www.ncbi.nlm.nih.gov/pubmed/16895441 http://dx.doi.org/10.1371/journal.pbio.0040261

Ejemplares similares

In Vivo Analysis of Conserved C. elegans Tomosyn Domains
por: Burdina, Anna O., et al.
Publicado: (2011)

Differential Regulation of Synaptic Vesicle Tethering and Docking by UNC-18 and TOM-1
por: Gracheva, Elena O., et al.
Publicado: (2010)

A Monoclonal Antibody Toolkit for C. elegans
por: Hadwiger, Gayla, et al.
Publicado: (2010)

UNC-13L, UNC-13S, and Tomosyn form a protein code for fast and slow neurotransmitter release in Caenorhabditis elegans
por: Hu, Zhitao, et al.
Publicado: (2013)

TOM-1/tomosyn acts with the UNC-6/netrin receptor UNC-5 to inhibit growth cone protrusion in Caenorhabditis elegans
por: Mahadik, Snehal S., et al.
Publicado: (2023)

Sentryn Acts with a Subset of Active Zone Proteins To Optimize the Localization of Synaptic Vesicles in Caenorhabditis elegans
por: Edwards, Stacey L., et al.
Publicado: (2018)

The decoy SNARE Tomosyn sets tonic versus phasic release properties and is required for homeostatic synaptic plasticity
por: Sauvola, Chad W, et al.
Publicado: (2021)

High-Throughput All-Optical Analysis of Synaptic Transmission and Synaptic Vesicle Recycling in Caenorhabditis elegans
por: Wabnig, Sebastian, et al.
Publicado: (2015)

The Caenorhabditis elegans microtubule minus-end binding homolog PTRN-1 stabilizes synapses and neurites
por: Marcette, Jana Dorfman, et al.
Publicado: (2014)

Tomosyn affects dense core vesicle composition but not exocytosis in mammalian neurons
por: Subkhangulova, Aygul, et al.
Publicado: (2023)

Age-dependent accumulation of tau aggregation in Caenorhabditis elegans
por: Aquino Nunez, Wendy, et al.
Publicado: (2022)

Differential Roles for Snapin and Synaptotagmin in the Synaptic Vesicle Cycle
por: Yu, Szi-Chieh, et al.
Publicado: (2013)

μ2 adaptin facilitates but is not essential for synaptic vesicle recycling in Caenorhabditis elegans
por: Gu, Mingyu, et al.
Publicado: (2008)

Intracellular Trafficking and Synaptic Function of APL-1 in Caenorhabditis elegans
por: Wiese, Mary, et al.
Publicado: (2010)

UNC-41/Stonin Functions with AP2 to Recycle Synaptic Vesicles in Caenorhabditis elegans
por: Mullen, Gregory P., et al.
Publicado: (2012)

Regulation of SNAREs by tomosyn and ROCK: implication in extension and retraction of neurites
por: Sakisaka, Toshiaki, et al.
Publicado: (2004)

Tomosyn Interacts with the SUMO E3 Ligase PIASγ
por: Geerts, Cornelia J., et al.
Publicado: (2014)

A conserved juxtacrine signal regulates synaptic partner recognition in Caenorhabditis elegans
por: Park, Joori, et al.
Publicado: (2011)

Tomosyn associates with secretory vesicles in neurons through its N- and C-terminal domains
por: Geerts, Cornelia J., et al.
Publicado: (2017)

The Caenorhabditis elegans vab-10 spectraplakin isoforms protect the epidermis against internal and external forces
por: Bosher, Julia M., et al.
Publicado: (2003)

Gene Expression of Caenorhabditis elegans Neurons Carries Information on Their Synaptic Connectivity
por: Kaufman, Alon, et al.
Publicado: (2006)

Endophilin A and B Join Forces With Clathrin to Mediate Synaptic Vesicle Recycling in Caenorhabditis elegans
por: Yu, Szi-chieh, et al.
Publicado: (2018)

Using Microarrays to Facilitate Positional Cloning: Identification of Tomosyn as an Inhibitor of Neurosecretion
por: Dybbs, Michael, et al.
Publicado: (2005)

Wild-type Caenorhabditis elegans isolates exhibit distinct gene expression profiles in response to microbial infection
por: Lansdon, Patrick, et al.
Publicado: (2022)

Heterodimerization of UNC-13/RIM regulates synaptic vesicle release probability but not priming in C. elegans
por: Liu, Haowen, et al.
Publicado: (2019)

Molecular Mechanisms Directing Spine Outgrowth and Synaptic Partner Selection in Caenorhabditis elegans
por: Oliver, Devyn, et al.
Publicado: (2018)

Novel Mutations in Synaptic Transmission Genes Suppress Neuronal Hyperexcitation in Caenorhabditis elegans
por: McCulloch, Katherine A., et al.
Publicado: (2017)

Differential regulation of polarized synaptic vesicle trafficking and synapse stability in neural circuit rewiring in Caenorhabditis elegans
por: Kurup, Naina, et al.
Publicado: (2017)

Draft Genome Sequence of Novel Staphylococcus epidermidis Strain EVL2000, Exhibiting Pathogenicity against Caenorhabditis elegans
por: Do, Nathan, et al.
Publicado: (2022)

Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release
por: Sakisaka, Toshiaki, et al.
Publicado: (2008)

Tomosyn Expression Pattern in the Mouse Hippocampus Suggests Both Presynaptic and Postsynaptic Functions
por: Barak, Boaz, et al.
Publicado: (2010)

Caenorhabditis Elegans
Publicado: (2000)

Additional Landing Sites for Recombination-Mediated Cassette Exchange in C. elegans
por: Nonet, Michael
Publicado: (2021)

Impaired dense core vesicle maturation in Caenorhabditis elegans mutants lacking Rab2
por: Edwards, Stacey L., et al.
Publicado: (2009)

Using Expression Profiles of Caenorhabditis elegans Neurons To Identify Genes That Mediate Synaptic Connectivity
por: Baruch, Leehod, et al.
Publicado: (2008)

Synaptic Polarity Depends on Phosphatidylinositol Signaling Regulated by myo-Inositol Monophosphatase in Caenorhabditis elegans
por: Kimata, Tsubasa, et al.
Publicado: (2012)

Wnts Promote Synaptic Assembly Through T-Cell Specific Transcription Factors in Caenorhabditis elegans
por: Shi, Yanjun, et al.
Publicado: (2018)

The synaptic organization in the Caenorhabditis elegans neural network suggests significant local compartmentalized computations
por: Ruach, Rotem, et al.
Publicado: (2023)

Improved GAL4 and Tet OFF drivers for C. elegans bipartite expression
por: Nonet, Michael
Publicado: (2021)

Rapid Redistribution of Synaptic PSD-95 in the Neocortex In Vivo
por: Gray, Noah W, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_q4u92hciea828nuvcvi09ae779