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M6P/IGF2R loss of heterozygosity in head and neck cancer associated with poor patient prognosis

BACKGROUND: The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) encodes for a multifunctional receptor involved in lysosomal enzyme trafficking, fetal organogenesis, cytotoxic T cell-induced apoptosis and tumor suppression. The purpose of this investigation was to determine if...

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Detalles Bibliográficos
Autores principales: Jamieson, Timothy A, Brizel, David M, Killian, J Keith, Oka, Yoshihiko, Jang, Hong-Seok, Fu, Xiaolong, Clough, Robert W, Vollmer, Robin T, Anscher, Mitchell S, Jirtle, Randy L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151601/
https://www.ncbi.nlm.nih.gov/pubmed/12589712
http://dx.doi.org/10.1186/1471-2407-3-4