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Transfection of IL-10 expression vectors into endothelial cultures attenuates α4β7-dependent lymphocyte adhesion mediated by MAdCAM-1

BACKGROUND: Enhanced expression of MAdCAM-1 (mucosal addressin cell adhesion molecule-1) is associated with the onset and progression of inflammatory bowel disease. The clinical significance of elevated MAdCAM-1 expression is supported by studies showing that immunoneutralization of MAdCAM-1, or its...

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Detalles Bibliográficos
Autores principales:	Sasaki, Makoto, Jordan, Paul, Houghton, Jeff, Meng, Xianmin, Itoh, Makoto, Joh, Takashi, Alexander, J Steven
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2003
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151603/ https://www.ncbi.nlm.nih.gov/pubmed/12625840 http://dx.doi.org/10.1186/1471-230X-3-3

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