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Chemical and biomechanical characterization of hyperhomocysteinemic bone disease in an animal model
BACKGROUND: Classical homocystinuria is an autosomal recessive disorder caused by cystathionine β-synthase (CBS) deficiency and characterized by distinctive alterations of bone growth and skeletal development. Skeletal changes include a reduction in bone density, making it a potentially attractive m...
Autores principales: | Massé, Priscilla G, Boskey, Adele L, Ziv, Israel, Hauschka, Peter, Donovan, Sharon M, Howell, David S, Cole, David EC |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151688/ https://www.ncbi.nlm.nih.gov/pubmed/12597778 http://dx.doi.org/10.1186/1471-2474-4-2 |
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