Cargando…

A technique to expose animals to concentrated fine ambient aerosols.

This paper presents the development and evaluation of an ambient particle concentrator for conducting animal inhalation exposure studies. The system utilizes the principle of virtual impactors to concentrate ambient particles in the size range 0.1-2.5 microns (aerodynamic diameter; dp) by drawing th...

Descripción completa

Detalles Bibliográficos
Autores principales: Sioutas, C, Koutrakis, P, Burton, R M
Formato: Texto
Lenguaje:English
Publicado: 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519008/
https://www.ncbi.nlm.nih.gov/pubmed/7737066
_version_ 1782128566910058496
author Sioutas, C
Koutrakis, P
Burton, R M
author_facet Sioutas, C
Koutrakis, P
Burton, R M
author_sort Sioutas, C
collection PubMed
description This paper presents the development and evaluation of an ambient particle concentrator for conducting animal inhalation exposure studies. The system utilizes the principle of virtual impactors to concentrate ambient particles in the size range 0.1-2.5 microns (aerodynamic diameter; dp) by drawing them through a series of three virtual impactors. Each impactor contains the majority of ambient fine mass (dp < 2.5 microns aerodynamic diameter) in a bleed flow (minor flow) that is 20% of the total flow entering the virtual impactor. The virtual impactors have been characterized using indoor air samples as test aerosols. Fine mass and sulfate concentrations at the outlet of the concentrating system were compared to the ambient fine mass and sulfate levels, which were determined using Harvard-Marple impactors. In each of the stages, particle concentration was increased by a factor of approximately 3. Thus, an overall concentration factor of about 25-30 was achieved. The main goal of this study was to demonstrate the feasibility of conducting animal exposures using the newly developed ambient fine particle concentrator.
format Text
id pubmed-1519008
institution National Center for Biotechnology Information
language English
publishDate 1995
record_format MEDLINE/PubMed
spelling pubmed-15190082006-07-28 A technique to expose animals to concentrated fine ambient aerosols. Sioutas, C Koutrakis, P Burton, R M Environ Health Perspect Research Article This paper presents the development and evaluation of an ambient particle concentrator for conducting animal inhalation exposure studies. The system utilizes the principle of virtual impactors to concentrate ambient particles in the size range 0.1-2.5 microns (aerodynamic diameter; dp) by drawing them through a series of three virtual impactors. Each impactor contains the majority of ambient fine mass (dp < 2.5 microns aerodynamic diameter) in a bleed flow (minor flow) that is 20% of the total flow entering the virtual impactor. The virtual impactors have been characterized using indoor air samples as test aerosols. Fine mass and sulfate concentrations at the outlet of the concentrating system were compared to the ambient fine mass and sulfate levels, which were determined using Harvard-Marple impactors. In each of the stages, particle concentration was increased by a factor of approximately 3. Thus, an overall concentration factor of about 25-30 was achieved. The main goal of this study was to demonstrate the feasibility of conducting animal exposures using the newly developed ambient fine particle concentrator. 1995-02 /pmc/articles/PMC1519008/ /pubmed/7737066 Text en
spellingShingle Research Article
Sioutas, C
Koutrakis, P
Burton, R M
A technique to expose animals to concentrated fine ambient aerosols.
title A technique to expose animals to concentrated fine ambient aerosols.
title_full A technique to expose animals to concentrated fine ambient aerosols.
title_fullStr A technique to expose animals to concentrated fine ambient aerosols.
title_full_unstemmed A technique to expose animals to concentrated fine ambient aerosols.
title_short A technique to expose animals to concentrated fine ambient aerosols.
title_sort technique to expose animals to concentrated fine ambient aerosols.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519008/
https://www.ncbi.nlm.nih.gov/pubmed/7737066
work_keys_str_mv AT sioutasc atechniquetoexposeanimalstoconcentratedfineambientaerosols
AT koutrakisp atechniquetoexposeanimalstoconcentratedfineambientaerosols
AT burtonrm atechniquetoexposeanimalstoconcentratedfineambientaerosols
AT sioutasc techniquetoexposeanimalstoconcentratedfineambientaerosols
AT koutrakisp techniquetoexposeanimalstoconcentratedfineambientaerosols
AT burtonrm techniquetoexposeanimalstoconcentratedfineambientaerosols