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Using cell replication data in mathematical modeling in carcinogenesis.
Risk estimation involves the application of quantitative models of dose versus response to carcinogenicity data. Recent advances in biology, computing, and mathematics have led to the application of mathematically complicated, mechanistically based models of carcinogenesis to the estimation of risks...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519438/ https://www.ncbi.nlm.nih.gov/pubmed/8013428 |
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author | Portier, C J Kopp-Schneider, A Sherman, C D |
author_facet | Portier, C J Kopp-Schneider, A Sherman, C D |
author_sort | Portier, C J |
collection | PubMed |
description | Risk estimation involves the application of quantitative models of dose versus response to carcinogenicity data. Recent advances in biology, computing, and mathematics have led to the application of mathematically complicated, mechanistically based models of carcinogenesis to the estimation of risks. This paper focuses on two aspects of this application, distinguishing between models using available data and the development of new models to keep pace with research developments. |
format | Text |
id | pubmed-1519438 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1993 |
record_format | MEDLINE/PubMed |
spelling | pubmed-15194382006-07-26 Using cell replication data in mathematical modeling in carcinogenesis. Portier, C J Kopp-Schneider, A Sherman, C D Environ Health Perspect Research Article Risk estimation involves the application of quantitative models of dose versus response to carcinogenicity data. Recent advances in biology, computing, and mathematics have led to the application of mathematically complicated, mechanistically based models of carcinogenesis to the estimation of risks. This paper focuses on two aspects of this application, distinguishing between models using available data and the development of new models to keep pace with research developments. 1993-12 /pmc/articles/PMC1519438/ /pubmed/8013428 Text en |
spellingShingle | Research Article Portier, C J Kopp-Schneider, A Sherman, C D Using cell replication data in mathematical modeling in carcinogenesis. |
title | Using cell replication data in mathematical modeling in carcinogenesis. |
title_full | Using cell replication data in mathematical modeling in carcinogenesis. |
title_fullStr | Using cell replication data in mathematical modeling in carcinogenesis. |
title_full_unstemmed | Using cell replication data in mathematical modeling in carcinogenesis. |
title_short | Using cell replication data in mathematical modeling in carcinogenesis. |
title_sort | using cell replication data in mathematical modeling in carcinogenesis. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519438/ https://www.ncbi.nlm.nih.gov/pubmed/8013428 |
work_keys_str_mv | AT portiercj usingcellreplicationdatainmathematicalmodelingincarcinogenesis AT koppschneidera usingcellreplicationdatainmathematicalmodelingincarcinogenesis AT shermancd usingcellreplicationdatainmathematicalmodelingincarcinogenesis |