Effects of inhaled alpha-emitting actinides on mouse alveolar macrophages.

The effects of inhaled alpha-emitting actinides on the alveolar macrophage (AM) population of the rodent lung are reviewed and, in particular, of the effects of 239PuO2 on murine AM. The effects discussed include changes the AM pool size, macrophage diameter, mobility, phagocytic competence, and enz...

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Detalles Bibliográficos
Autores principales: Morgan, A, Talbot, R J
Formato: Texto
Lenguaje:English
Publicado: 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519550/
https://www.ncbi.nlm.nih.gov/pubmed/1327735
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author Morgan, A
Talbot, R J
author_facet Morgan, A
Talbot, R J
author_sort Morgan, A
collection PubMed
description The effects of inhaled alpha-emitting actinides on the alveolar macrophage (AM) population of the rodent lung are reviewed and, in particular, of the effects of 239PuO2 on murine AM. The effects discussed include changes the AM pool size, macrophage diameter, mobility, phagocytic competence, and enzyme content. Finally, similarities in the dose-response relationships for the induction of nuclear aberrations by alpha emitters and in the induction of lung tumors by the same materials are noted.
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spelling pubmed-15195502006-07-26 Effects of inhaled alpha-emitting actinides on mouse alveolar macrophages. Morgan, A Talbot, R J Environ Health Perspect Research Article The effects of inhaled alpha-emitting actinides on the alveolar macrophage (AM) population of the rodent lung are reviewed and, in particular, of the effects of 239PuO2 on murine AM. The effects discussed include changes the AM pool size, macrophage diameter, mobility, phagocytic competence, and enzyme content. Finally, similarities in the dose-response relationships for the induction of nuclear aberrations by alpha emitters and in the induction of lung tumors by the same materials are noted. 1992-07 /pmc/articles/PMC1519550/ /pubmed/1327735 Text en
spellingShingle Research Article
Morgan, A
Talbot, R J
Effects of inhaled alpha-emitting actinides on mouse alveolar macrophages.
title Effects of inhaled alpha-emitting actinides on mouse alveolar macrophages.
title_full Effects of inhaled alpha-emitting actinides on mouse alveolar macrophages.
title_fullStr Effects of inhaled alpha-emitting actinides on mouse alveolar macrophages.
title_full_unstemmed Effects of inhaled alpha-emitting actinides on mouse alveolar macrophages.
title_short Effects of inhaled alpha-emitting actinides on mouse alveolar macrophages.
title_sort effects of inhaled alpha-emitting actinides on mouse alveolar macrophages.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519550/
https://www.ncbi.nlm.nih.gov/pubmed/1327735
work_keys_str_mv AT morgana effectsofinhaledalphaemittingactinidesonmousealveolarmacrophages
AT talbotrj effectsofinhaledalphaemittingactinidesonmousealveolarmacrophages

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