Detection of ras gene mutations in human lung cancer: comparison of two screening assays based on the polymerase chain reaction.

We studied the prevalence of point mutations in ras oncogenes (K-ras and N-ras) in DNA from white blood cells and tumor tissue from 36 untreated patients with non-small-cell lung cancer, all of whom were smokers or ex-smokers. We observed somatic K-ras mutations in one-third of the lung carcinomas s...

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Detalles Bibliográficos
Autores principales: Husgafvel-Pursiainen, K, Ridanpää, M, Hackman, P, Anttila, S, Karjalainen, A, Onfelt, A, Børresen, A L, Vainio, H
Formato: Texto
Lenguaje:English
Publicado: 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519635/
https://www.ncbi.nlm.nih.gov/pubmed/1486847

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