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Mechanistic relationship among mutagenicity, skin sensitization, and skin carcinogenicity.
Twenty organic Salmonella mutagens, seven of which (including benzo[a]pyrene) are established skin carcinogens, and one of which (2-chloroethanol) is a well-defined noncarcinogen to skin, have been evaluated for skin-sensitizing activity using the local lymph node assay. The relative mutagenicity of...
Autores principales: | Ashby, J, Hilton, J, Dearman, R J, Callander, R D, Kimber, I |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519640/ https://www.ncbi.nlm.nih.gov/pubmed/8513766 |
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