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Characterization of acute 4,4'-methylene dianiline hepatotoxicity in the rat.
Methylene dianiline (DDM) is a chemical intermediate in the production of isocyanates and other industrial chemicals, and it is hepatotoxic in humans. The acute hepatotoxicity of orally administered DDM was characterized in rats. Rats receiving DDM (25-225 mg/kg, per os) demonstrated a dose-dependen...
Autores principales: | Bailie, M B, Mullaney, T P, Roth, R A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519728/ https://www.ncbi.nlm.nih.gov/pubmed/8354198 |
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