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A 39-year follow-up of the U.K. oil refinery and distribution center studies: results for kidney cancer and leukemia.

This paper presents briefly some of the principal results of a mortality analysis of a cohort of workers employed for at least 1 year between 1950 and 1975 at eight oil refineries and approximately 750 distribution centers in the U.K., together with detailed results for kidney cancer and leukemia. O...

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Autor principal: Rushton, L
Formato: Texto
Lenguaje:English
Publicado: 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1520001/
https://www.ncbi.nlm.nih.gov/pubmed/8020451
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author Rushton, L
author_facet Rushton, L
author_sort Rushton, L
collection PubMed
description This paper presents briefly some of the principal results of a mortality analysis of a cohort of workers employed for at least 1 year between 1950 and 1975 at eight oil refineries and approximately 750 distribution centers in the U.K., together with detailed results for kidney cancer and leukemia. Over 99% of the workers were successfully traced. Their mortality was compared with that of all males in the national population. The mortality from all causes of death is lower than that of the comparison population in both studies, and reduced mortality is also found for many of the major nonmalignant causes of death. In the refinery study, some increased mortality patterns are found for diseases of the arteries, and no healthy worker effect is found in the distribution center study for ischemic heart disease. Mortality from all neoplasms is lower than expected overall in both studies, largely due to a deficit of deaths from malignant neoplasm of the lung. Mortality from malignant neoplasm of the kidney is increased overall in the distribution center study, and in drivers in particular. The mortality from this disease increases with increased time since first exposure. The observed deaths from leukemia are slightly less than expected in the refinery study and slightly more than expected in the distribution center study. One refinery shows increased mortality due to in myeloid leukemia, and mortality is increased among refinery operators. Mortality is also raised in distribution center drivers, particularly for myeloid leukemias, including acute myeloid leukemia.
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spelling pubmed-15200012006-07-26 A 39-year follow-up of the U.K. oil refinery and distribution center studies: results for kidney cancer and leukemia. Rushton, L Environ Health Perspect Research Article This paper presents briefly some of the principal results of a mortality analysis of a cohort of workers employed for at least 1 year between 1950 and 1975 at eight oil refineries and approximately 750 distribution centers in the U.K., together with detailed results for kidney cancer and leukemia. Over 99% of the workers were successfully traced. Their mortality was compared with that of all males in the national population. The mortality from all causes of death is lower than that of the comparison population in both studies, and reduced mortality is also found for many of the major nonmalignant causes of death. In the refinery study, some increased mortality patterns are found for diseases of the arteries, and no healthy worker effect is found in the distribution center study for ischemic heart disease. Mortality from all neoplasms is lower than expected overall in both studies, largely due to a deficit of deaths from malignant neoplasm of the lung. Mortality from malignant neoplasm of the kidney is increased overall in the distribution center study, and in drivers in particular. The mortality from this disease increases with increased time since first exposure. The observed deaths from leukemia are slightly less than expected in the refinery study and slightly more than expected in the distribution center study. One refinery shows increased mortality due to in myeloid leukemia, and mortality is increased among refinery operators. Mortality is also raised in distribution center drivers, particularly for myeloid leukemias, including acute myeloid leukemia. 1993-12 /pmc/articles/PMC1520001/ /pubmed/8020451 Text en
spellingShingle Research Article
Rushton, L
A 39-year follow-up of the U.K. oil refinery and distribution center studies: results for kidney cancer and leukemia.
title A 39-year follow-up of the U.K. oil refinery and distribution center studies: results for kidney cancer and leukemia.
title_full A 39-year follow-up of the U.K. oil refinery and distribution center studies: results for kidney cancer and leukemia.
title_fullStr A 39-year follow-up of the U.K. oil refinery and distribution center studies: results for kidney cancer and leukemia.
title_full_unstemmed A 39-year follow-up of the U.K. oil refinery and distribution center studies: results for kidney cancer and leukemia.
title_short A 39-year follow-up of the U.K. oil refinery and distribution center studies: results for kidney cancer and leukemia.
title_sort 39-year follow-up of the u.k. oil refinery and distribution center studies: results for kidney cancer and leukemia.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1520001/
https://www.ncbi.nlm.nih.gov/pubmed/8020451
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