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Computerized image analysis for determining micronucleus frequency.

A method for the computerized automation of micronucleus scoring is presented. The task is to identify the cultured, cytokinesis-blocked peripheral lymphocytes (CB cells) and their micronuclei (MN). The main parts of the hardware are the video camera attached to the microscope, the IBM-compatible pe...

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Detalles Bibliográficos
Autores principales: Szirmai, S, Bérces, J, Köteles, G J
Formato: Texto
Lenguaje:English
Publicado: 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1521116/
https://www.ncbi.nlm.nih.gov/pubmed/8143648
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author Szirmai, S
Bérces, J
Köteles, G J
author_facet Szirmai, S
Bérces, J
Köteles, G J
author_sort Szirmai, S
collection PubMed
description A method for the computerized automation of micronucleus scoring is presented. The task is to identify the cultured, cytokinesis-blocked peripheral lymphocytes (CB cells) and their micronuclei (MN). The main parts of the hardware are the video camera attached to the microscope, the IBM-compatible personal computer with the video digitizer card, and the computer-controlled stage movement unit. The computerized image processing is based on determination and interpretation of contour lines of the CB cells, nuclei, and MN. The BNCTEST image processing software has been developed up to the demonstration phase, and now it has been prepared for the testing period of image series on a large scale.
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spelling pubmed-15211162006-07-26 Computerized image analysis for determining micronucleus frequency. Szirmai, S Bérces, J Köteles, G J Environ Health Perspect Research Article A method for the computerized automation of micronucleus scoring is presented. The task is to identify the cultured, cytokinesis-blocked peripheral lymphocytes (CB cells) and their micronuclei (MN). The main parts of the hardware are the video camera attached to the microscope, the IBM-compatible personal computer with the video digitizer card, and the computer-controlled stage movement unit. The computerized image processing is based on determination and interpretation of contour lines of the CB cells, nuclei, and MN. The BNCTEST image processing software has been developed up to the demonstration phase, and now it has been prepared for the testing period of image series on a large scale. 1993-10 /pmc/articles/PMC1521116/ /pubmed/8143648 Text en
spellingShingle Research Article
Szirmai, S
Bérces, J
Köteles, G J
Computerized image analysis for determining micronucleus frequency.
title Computerized image analysis for determining micronucleus frequency.
title_full Computerized image analysis for determining micronucleus frequency.
title_fullStr Computerized image analysis for determining micronucleus frequency.
title_full_unstemmed Computerized image analysis for determining micronucleus frequency.
title_short Computerized image analysis for determining micronucleus frequency.
title_sort computerized image analysis for determining micronucleus frequency.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1521116/
https://www.ncbi.nlm.nih.gov/pubmed/8143648
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