A perspective on nonmutagenic mechanisms in carcinogenesis.

Although there is compelling evidence for multiple mutagenic events in the induction of cancers, there is also substantial evidence in support of nonmutagenic mechanisms. It is proposed that the genetic basis of noninduced or spontaneous tumors, as well as cancers induced by nonmutagens, involves he...

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Detalles Bibliográficos
Autor principal: Tennant, R W
Formato: Texto
Lenguaje:English
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1521175/
https://www.ncbi.nlm.nih.gov/pubmed/8143623
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author Tennant, R W
author_facet Tennant, R W
author_sort Tennant, R W
collection PubMed
description Although there is compelling evidence for multiple mutagenic events in the induction of cancers, there is also substantial evidence in support of nonmutagenic mechanisms. It is proposed that the genetic basis of noninduced or spontaneous tumors, as well as cancers induced by nonmutagens, involves heritable changes in the regulation of gene expression.
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spelling pubmed-15211752006-07-26 A perspective on nonmutagenic mechanisms in carcinogenesis. Tennant, R W Environ Health Perspect Research Article Although there is compelling evidence for multiple mutagenic events in the induction of cancers, there is also substantial evidence in support of nonmutagenic mechanisms. It is proposed that the genetic basis of noninduced or spontaneous tumors, as well as cancers induced by nonmutagens, involves heritable changes in the regulation of gene expression. 1993-10 /pmc/articles/PMC1521175/ /pubmed/8143623 Text en
spellingShingle Research Article
Tennant, R W
A perspective on nonmutagenic mechanisms in carcinogenesis.
title A perspective on nonmutagenic mechanisms in carcinogenesis.
title_full A perspective on nonmutagenic mechanisms in carcinogenesis.
title_fullStr A perspective on nonmutagenic mechanisms in carcinogenesis.
title_full_unstemmed A perspective on nonmutagenic mechanisms in carcinogenesis.
title_short A perspective on nonmutagenic mechanisms in carcinogenesis.
title_sort perspective on nonmutagenic mechanisms in carcinogenesis.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1521175/
https://www.ncbi.nlm.nih.gov/pubmed/8143623
work_keys_str_mv AT tennantrw aperspectiveonnonmutagenicmechanismsincarcinogenesis
AT tennantrw perspectiveonnonmutagenicmechanismsincarcinogenesis

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