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Structural Organization of the 19S Proteasome Lid: Insights from MS of Intact Complexes
The 26S proteasome contains a 19S regulatory particle that selects and unfolds ubiquitinated substrates for degradation in the 20S catalytic particle. To date there are no high-resolution structures of the 19S assembly, nor of the lid or base subcomplexes that constitute the 19S. Mass spectra of the...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523230/ https://www.ncbi.nlm.nih.gov/pubmed/16869714 http://dx.doi.org/10.1371/journal.pbio.0040267 |