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Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study
BACKGROUND: Alpha-defensins, which are major constituents of neutrophil azurophilic granules, and beta-defensins, which are expressed in airway epithelial cells, could contribute to the pathogenesis of chronic obstructive pulmonary disease by amplifying cigarette smoke-induced and infection-induced...
Autores principales: | Wallace, Alison M, He, Jian-Qing, Burkett, Kelly M, Ruan, Jian, Connett, John E, Anthonisen, Nicholas R, Paré, Peter D, Sandford, Andrew J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523340/ https://www.ncbi.nlm.nih.gov/pubmed/16700921 http://dx.doi.org/10.1186/1465-9921-7-76 |
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