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Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission

BACKGROUND: Microbicides must protect against STD pathogens without causing unacceptable toxic effects. Microbicides based on nonoxynol-9 (N9) and other detergents disrupt sperm, HSV and HIV membranes, and these agents are effective contraceptives. But paradoxically N9 fails to protect women against...

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Detalles Bibliográficos
Autores principales:	Cone, Richard A, Hoen, Timothy, Wong, XiXi, Abusuwwa, Raed, Anderson, Deborah J, Moench, Thomas R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523343/ https://www.ncbi.nlm.nih.gov/pubmed/16740164 http://dx.doi.org/10.1186/1471-2334-6-90

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