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Multivariable risk prediction can greatly enhance the statistical power of clinical trial subgroup analysis
BACKGROUND: When subgroup analyses of a positive clinical trial are unrevealing, such findings are commonly used to argue that the treatment's benefits apply to the entire study population; however, such analyses are often limited by poor statistical power. Multivariable risk-stratified analysi...
Autores principales: | Hayward, Rodney A, Kent, David M, Vijan, Sandeep, Hofer, Timothy P |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523355/ https://www.ncbi.nlm.nih.gov/pubmed/16613605 http://dx.doi.org/10.1186/1471-2288-6-18 |
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