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Efficacy and tolerability of gemtuzumab ozogamicin (anti-CD33 monoclonal antibody, CMA-676, Mylotarg(®)) in children with relapsed/refractory myeloid leukemia

BACKGROUND: Gemtuzumab ozogamicin (GO) is a cytotoxic anti-CD33 monoclonal antibody that has given promising preliminary results in adult myeloid CD33+ AML. We conducted a retrospective multicenter study of 12 children treated with GO on a compassionate basis (median age 5.5 y). Three patients (2 MD...

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Detalles Bibliográficos
Autores principales:	Brethon, Benoit, Auvrignon, Anne, Galambrun, Claire, Yakouben, Karima, Leblanc, Thierry, Bertrand, Yves, Leverger, Guy, Baruchel, André
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523361/ https://www.ncbi.nlm.nih.gov/pubmed/16805911 http://dx.doi.org/10.1186/1471-2407-6-172

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