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Perforated gastric carcinoma: a report of 10 cases and review of the literature
BACKGROUND: Perforation is a rare complication of gastric carcinoma, accounting for less than 1% of all gastric cancer cases. The aim of the present study is to evaluate the prognostic value of perforation and to point out the surgical treatment options. METHODS: A total of 10 patients with perforat...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524767/ https://www.ncbi.nlm.nih.gov/pubmed/16573818 http://dx.doi.org/10.1186/1477-7819-4-19 |
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author | Roviello, Franco Rossi, Simone Marrelli, Daniele De Manzoni, Giovanni Pedrazzani, Corrado Morgagni, Paolo Corso, Giovanni Pinto, Enrico |
author_facet | Roviello, Franco Rossi, Simone Marrelli, Daniele De Manzoni, Giovanni Pedrazzani, Corrado Morgagni, Paolo Corso, Giovanni Pinto, Enrico |
author_sort | Roviello, Franco |
collection | PubMed |
description | BACKGROUND: Perforation is a rare complication of gastric carcinoma, accounting for less than 1% of all gastric cancer cases. The aim of the present study is to evaluate the prognostic value of perforation and to point out the surgical treatment options. METHODS: A total of 10 patients with perforated gastric carcinoma were retrospectively reviewed among 2564 consecutive cases of gastric cancer operated in three Centers belonging to the Italian Research Group for Gastric Cancer. The clinicopathological features including tumor stage and survival were analyzed and compared to literature data. RESULTS: Incidence rate was 0.39%. All patients underwent emergency surgery, being performed gastrectomy in 6 patients (mortality 17%) and repair surgery in 4 patients (mortality 75%). The survival of patients was related to the stage of the disease, with 2 long-survival cases. CONCLUSION: Perforation usually occurs in advanced stages of gastric cancer; nevertheless surgeons should not be always discouraged from a radical treatment of perforated gastric cancer, since perforation even occurs in early stages and seems not to be a negative prognostic factor itself. When possible, emergency gastrectomy should be performed, leaving repair surgery for unresectable tumors. A two-stage treatment is a good treatment option for frail patients with resectable tumors. |
format | Text |
id | pubmed-1524767 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-15247672006-07-29 Perforated gastric carcinoma: a report of 10 cases and review of the literature Roviello, Franco Rossi, Simone Marrelli, Daniele De Manzoni, Giovanni Pedrazzani, Corrado Morgagni, Paolo Corso, Giovanni Pinto, Enrico World J Surg Oncol Research BACKGROUND: Perforation is a rare complication of gastric carcinoma, accounting for less than 1% of all gastric cancer cases. The aim of the present study is to evaluate the prognostic value of perforation and to point out the surgical treatment options. METHODS: A total of 10 patients with perforated gastric carcinoma were retrospectively reviewed among 2564 consecutive cases of gastric cancer operated in three Centers belonging to the Italian Research Group for Gastric Cancer. The clinicopathological features including tumor stage and survival were analyzed and compared to literature data. RESULTS: Incidence rate was 0.39%. All patients underwent emergency surgery, being performed gastrectomy in 6 patients (mortality 17%) and repair surgery in 4 patients (mortality 75%). The survival of patients was related to the stage of the disease, with 2 long-survival cases. CONCLUSION: Perforation usually occurs in advanced stages of gastric cancer; nevertheless surgeons should not be always discouraged from a radical treatment of perforated gastric cancer, since perforation even occurs in early stages and seems not to be a negative prognostic factor itself. When possible, emergency gastrectomy should be performed, leaving repair surgery for unresectable tumors. A two-stage treatment is a good treatment option for frail patients with resectable tumors. BioMed Central 2006-03-30 /pmc/articles/PMC1524767/ /pubmed/16573818 http://dx.doi.org/10.1186/1477-7819-4-19 Text en Copyright © 2006 Roviello et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Roviello, Franco Rossi, Simone Marrelli, Daniele De Manzoni, Giovanni Pedrazzani, Corrado Morgagni, Paolo Corso, Giovanni Pinto, Enrico Perforated gastric carcinoma: a report of 10 cases and review of the literature |
title | Perforated gastric carcinoma: a report of 10 cases and review of the literature |
title_full | Perforated gastric carcinoma: a report of 10 cases and review of the literature |
title_fullStr | Perforated gastric carcinoma: a report of 10 cases and review of the literature |
title_full_unstemmed | Perforated gastric carcinoma: a report of 10 cases and review of the literature |
title_short | Perforated gastric carcinoma: a report of 10 cases and review of the literature |
title_sort | perforated gastric carcinoma: a report of 10 cases and review of the literature |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524767/ https://www.ncbi.nlm.nih.gov/pubmed/16573818 http://dx.doi.org/10.1186/1477-7819-4-19 |
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