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Association between disruption of CD4 receptor dimerization and increased human immunodeficiency virus type 1 entry

BACKGROUND: Human immunodeficiency virus (HIV) enters target cells by a membrane fusion process that involves a series of sequential interactions between its envelope glycoproteins, the CD4 receptor and CXCR4/CCR5 coreceptors. CD4 molecules are expressed at the cell surface of lymphocytes and monocy...

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Detalles Bibliográficos
Autores principales: Bourgeois, Rachel, Mercier, Johanne, Paquette-Brooks, Isabelle, Cohen, Éric A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524797/
https://www.ncbi.nlm.nih.gov/pubmed/16762062
http://dx.doi.org/10.1186/1742-4690-3-31