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AUG sequences are required to sustain nonsense-codon-mediated suppression of splicing

More than 90% of human genes are rich in intronic latent 5′ splice sites whose utilization in pre-mRNA splicing would introduce in-frame stop codons into the resultant mRNAs. We have therefore hypothesized that suppression of splicing (SOS) at latent 5′ splice sites regulates alternative 5′ splice s...

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Detalles Bibliográficos
Autores principales: Kamhi, Eyal, Yahalom, Galit, Kass, Gideon, Hacham, Yael, Sperling, Ruth, Sperling, Joseph
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524910/
https://www.ncbi.nlm.nih.gov/pubmed/16855285
http://dx.doi.org/10.1093/nar/gkl390