H1 RNA polymerase III promoter-driven expression of an RNA aptamer leads to high-level inhibition of intracellular protein activity

Aptamers offer advantages over other oligonucleotide-based approaches that artificially interfere with target gene function due to their ability to bind protein products of these genes with high affinity and specificity. However, RNA aptamers are limited in their ability to target intracellular prot...

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Detalles Bibliográficos
Autores principales: Mi, Jing, Zhang, Xiuwu, Rabbani, Zahid N, Liu, Yingmiao, Su, Zhen, Vujaskovic, Zeljko, Kontos, Christopher D., Sullenger, Bruce A., Clary, Bryan M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524923/
https://www.ncbi.nlm.nih.gov/pubmed/16855294
http://dx.doi.org/10.1093/nar/gkl482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524923/
https://www.ncbi.nlm.nih.gov/pubmed/16855294
http://dx.doi.org/10.1093/nar/gkl482

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