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Identification of the hASCT2-binding domain of the Env ERVWE1/syncytin-1 fusogenic glycoprotein

The cellular HERV-W envelope/syncytin-1 protein, encoded by the envelope gene of the ERVWE1 proviral locus is a fusogenic glycoprotein probably involved in the formation of the placental syncytiotrophoblast layer. Syncytin-1-induced in vitro cell-cell fusion is dependent on the interaction with hASC...

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Detalles Bibliográficos
Autores principales: Cheynet, Valérie, Oriol, Guy, Mallet, François
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524976/
https://www.ncbi.nlm.nih.gov/pubmed/16820059
http://dx.doi.org/10.1186/1742-4690-3-41