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The role of HIF-1α in maintaining cartilage homeostasis and during the pathogenesis of osteoarthritis
As a consequence of the avascular nature of cartilage the microenvironment in which chondrocytes must exist is characterized by hostile conditions, most prominently very low levels of oxygen (hypoxia). In recent years, a vast number of papers reporting on the role of hypoxia in cartilage development...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526557/ https://www.ncbi.nlm.nih.gov/pubmed/16542470 http://dx.doi.org/10.1186/ar1894 |