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PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease

We analysed relationships between the PTPN22 1858 polymorphism and antibodies to cyclic citrullinated peptide (CCP), rheumatoid factors (RFs) and the shared epitope (SE) gene (HLA-DRB1*0404 or 0401) and determined their combined predictive value for rheumatoid arthritis (RA) in individuals who subse...

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Detalles Bibliográficos
Autores principales:	Johansson, Martin, Ärlestig, Lisbeth, Hallmans, Göran, Rantapää-Dahlqvist, Solbritt
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526580/ https://www.ncbi.nlm.nih.gov/pubmed/16507117 http://dx.doi.org/10.1186/ar1868

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