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Proteoglycan 4 downregulation in a sheep meniscectomy model of early osteoarthritis
Osteoarthritis is a disease of multifactorial aetiology characterised by progressive breakdown of articular cartilage. In the early stages of the disease, changes become apparent in the superficial zone of articular cartilage, including fibrillation and fissuring. Normally, a monolayer of lubricatin...
Autores principales: | Young, Allan A, McLennan, Susan, Smith, Margaret M, Smith, Susan M, Cake, Martin A, Read, Richard A, Melrose, James, Sonnabend, David H, Flannery, Carl R, Little, Christopher B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526595/ https://www.ncbi.nlm.nih.gov/pubmed/16469119 http://dx.doi.org/10.1186/ar1898 |
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