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Suppression of inflammation by low-dose methotrexate is mediated by adenosine A(2A )receptor but not A(3 )receptor activation in thioglycollate-induced peritonitis
Prior studies demonstrate that adenosine, acting at one or more of its receptors, mediates the anti-inflammatory effects of methotrexate in animal models of both acute and chronic inflammation. Both adenosine A(2A )and A(3 )receptors contribute to the anti-inflammatory effects of methotrexate treatm...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526598/ https://www.ncbi.nlm.nih.gov/pubmed/16519795 http://dx.doi.org/10.1186/ar1914 |